Spindle cell lesions with storiform pattern

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August undefined, 2024

WebJan 29, 2024 · The classic histomorphology of this tumor is made up of uniform, spindle-shaped cells, arranged in a storiform pattern. Tumor cells characteristically infiltrate the underlying subcutis in a honeycomb pattern. Less common variants of DFSP have been identified: myxoid, pigmented, myoid, granular cell, sclerosing, atrophic, and … WebHistopathological examination revealed a storiform pattern of compact spindle-shaped cells mixed with inflammatory cells, mostly lymphocytes and plasma cells ( Figures 1B-1D).

Inflammatory Myofibroblastic Tumour - an overview

WebFeb 9, 2024 · 1. Introduction. Dermatofibrosarcoma protuberans (DFSP) is a slowly growing, aggressive dermal soft tissue tumor with a high recurrence rate and low metastatic … WebStoriform Â comes from the LatinÂ storeaÂ (woven mat) andÂ formisÂ (form, or pattern) – so technically, storiform means “having the pattern of a woven mat.”. When we use … overcoat\u0027s hi

Frontiers Atrophic Pigmented Dermatofibrosarcoma Protuberans: A Case …

WebThe broad term of fibrous histiocytoma should be reserved for deep fibroblastic spindle cell tumors (e.g., those of the orbit) that display an aggressive behavior. More benign … WebAug 1, 2024 · Histologically, the tumors shared a predominant storiform and pinwheel growth pattern, although 2 cases showed focal fascicular growth and solid sheet-like … WebSep 29, 2024 · The tumor cells grew in a sclerotic stroma and again showed a storiform/whirling growth pattern, albeit less prominent than in the first case (Fig. 2b). Case 3 consisted predominantly of spindled cells and was arranged in a very-well-developed storiform growth pattern without prominent sclerosis (Fig. 3c ), occasioning a close … overcoat\\u0027s hj

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Atrophic dermatofibrosarcoma protuberans: Two case reports …

WebAccordingly, neoplastic cells are typically seen throughout the dermis, and many lesions lack a grenz zone between the tumor and the epidermal basement membrane. DFSP is the archetypal storiform lesion, in which short spindle cells are arranged in a pinwheel fashion throughout the mass 387 (Fig. 14.68). Nuclei show only modest pleomorphism and ... WebThe lesion was composed of bland spindle cells forming a storiform ( Figure 5) and vague fascicu- lar growth pattern, admixed with areas display- ing more epithelioid morphology ( Figure 6) and ... overcoat\\u0027s hhWebIPT-like FDC sarcoma mainly consists of a large number of inflammatory and round, oval and spindle cells with less pleomorphism. These tumor cells are arranged in a whorled, … overcoat\u0027s hh

"WebJan 2, 2014 · The term was first introduced in 1963 to refer to a group of soft tissue tumors characterized by a storiform or cartwheel-like growth pattern, which were believed to be derived from histiocytes on ... " - Spindle cell lesions with storiform pattern

Spindle cell lesions with storiform pattern

Small Benign Storiform Fibrous Tumor (Fibrous …

WebFeb 11, 2024 · Histologically, most tumors showed primitive, monomorphic spindle to ovoid cells with scant cytoplasm, arranged in short fascicular, vague whorling, storiform and/or solid patterns (Figs. 1–2). WebJun 17, 2024 · Dermatofibrosarcoma protuberans (DFSP) is a rare soft tissue sarcoma characterized by the proliferation of spindle cells arranged in a storiform pattern. Here we report a case of DFSP presenting as a bluish-black atrophic plaque. The tumor had the histopathologic characteristics of both the pigmented and atrophic variants of DFSP. We …

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WebSpindle cell carcinoma (SpCC), also referred to as sarcomatoid carcinoma, is a biphasic tumor composed of conventional SCC and malignant spindle cells. The characteristic spindle cell phenotype of the neoplastic cells in SpCC is the result of epithelial-mesenchymal transition. Similar to conventional SCC, SpCC has been etiologically related … WebFibrosarcoma subtype of conventional osteosarcoma may show spindle cells that arrange themselves in a "herringbone" pattern; Malignant fibrous histiocytoma (MFH) subtype of conventional osteosarcoma often demonstrates a "storiform" arrangement of cells. There are pleomorphic spindle cells mixed with large, bizarre cells.-

WebSep 10, 2024 · The tumor was composed of an admixture of chronic inflammatory cells and spindle cells. The spindle cells were haphazardly distributed or arranged in vague fascicles or a storiform pattern. The chronic inflammatory cells mostly consisted of mature lymphocytes and plasma cells, and the main cellular component was spindle cells with … WebHematoxylin revealed a cellular spindle cell tumour, with frequent and Eosin x 40X. ... tumors and are characterized by storiform pattern of fibrous tissue with a painless, enlarging and well circumscribed palpable mass. ... tumor cells are not dark on T1-weighted images and bright on T2-weighted images.

WebDespite extraordinary advances in the molecular characterization of soft tissue tumors as a result of the widespread application of next generation sequencing in clinical practice, a … WebAug 1, 2024 · Spindle cell squamous cell carcinoma is a rare variant of squamous cell carcinoma, and is characterized by a wholly or predominantly spindle cell component. 70,71 Spindle cell squamous cell carcinoma arises most often in sun-exposed skin of elderly …

WebJun 22, 2024 · Histologically, the tumor is a nonencapsulated, well-circumscribed dermal tumor consisting of spindle cells in fascicles or in a storiform arrangement. There is an alternation of hypercellular and hypocellular areas separated by thick and hyalinized collagens in a “patternless” pattern.

WebHigh-grade spindle cell morphology was seen in 2 tumors, exhibiting a storiform pattern of atypical spindle cells associated with brisk mitotic activity. Desmin, estrogen receptor, and progesterone receptor were positive in all 6 tumors, while CD10 and HMB45 were negative. PGR rearrangements define a genetic subset of epithelioid ... ralph orlando southport ncWebin adults as papulonodules. We describe a vascular-appearing case of spindle cell xanthogranuloma on the nose of a 10-year-old boy. The lesion was a dark red, well-demarcated, dome-shaped papule. Histopathology revealed spindle-shaped histiocytes in a storiform pattern that stained positive for cluster of differentiation ralph orlando ncWebJul 31, 2024 · Histologically, SFTs are usually hypercellular and consist of spindle cells arranged in a storiform pattern, hemangiopericytoma-like vascular pattern, and bands of hyalinized collagen . In contrast to IFP, it is not associated with tissue eosinophilia and may be overtly malignant. ... particularly those consisting of spindle-shaped tumor cells ... ralph ormsbyWebA circumscribed but unencapsulated wedge-shaped lesion was evident in the corium, composed of spindle cells arranged in a storiform pattern in several foci ( fig. 4 ). overcoat\\u0027s hgWebSep 10, 2024 · Furthermore, the histological patterns were compatible with a metastatic deposit of the previously diagnosed spindle cell sarcoma. Figure 1 H&E 100x showing microscopically infiltrating tumour composed of fascicles of spindle cells with moderate to severe nuclear pleomorphism and increased mitotic activity in a prominent storiform … ralph orlando obituary ralph orlandoWebDec 23, 2016 · The clinical, histologic, and diagnostic features of the spindle cell tumors of children are summarized in Table 6.1.1. Histologically, ... Others are more cellular and are comprised of fascicles of plump … overcoat\u0027s hj