Pho92 yeast
Webb16 sep. 2014 · Now we systematically characterized the binding affinities of the YTH domains of three other human proteins and yeast YTH domain protein Pho92 and … Webb8 aug. 2024 · We show that Pho92 is an early meiotic factor that promotes timely meiotic progression. High-throughput RNA sequencing and mapping of Pho92-binding sites following UV-crosslinking reveal that Pho92 is recruited to specific mRNAs in an m6A-dependent manner during the meiotic prophase, preceding their down-regulation.
Pho92 yeast
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WebbYeast PHO92 is homologous to human YTHDF2, and has been used to study disease of metabolism. Download All Annotations (.txt) Manually Curated . Manually curated DO annotations reflect our best understanding of disease association for … Webb1 apr. 2024 · Furthermore, the YTH domain of yeast Pho92, the only YTH domain-containing protein in Saccharomyces cerevisiae, adopts the canonical YTH fold and possesses the m 6 A-binding pocket (Figure 3 C) [46], which is formed by W177, W231, and Y237, suggesting a conserved m 6 A recognition mode in eukaryotes (Figure 3 C).
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WebbTo identify the exact mechanism of Pho92 action with respect to phosphate metabolism, we investigated the effect of Pho92 on PHO4 expression. The half-life of PHO4 mRNA was increased in the Δpho92 strain; this phenotype was also observed in the deletion mutants UPF1 and POP2 , which are components of the NMD (nonsense-mediated decay) … WebbIn this study, we systematically characterized the m 6 A binding ability of four human YTH domains and the YTH domain of yeast Pho92 and determined the crystal structures of the YTH domain of human YTHDF1 …
Webb22 okt. 2024 · The fission yeast Schizosaccharomyces pombe YTH domain containing protein Mmi1 could bind the specific mRNAs relating to meiosis and is responsible for removal of them [12]. The budding yeast Saccharomyces cerevisiae unique YTH domain containing protein Pho92 binding to 3′-UTR of the PHO4 mRNA which is responsible for …
Webb21 jan. 2024 · Pho92 is part of an mRNA fate control pathway for m6A modified mRNAs that is instated during transcription and couples translation efficacy to mRNA decay, and … circuit city ebayWebb11 dec. 2024 · PoYth1 is homologous to yeast Pho92 (E value: 3e-08), which contains a YTH domain and facilitates PHO4 mRNA degradation (Kang et al. 2014). Figure 1. Open … diamond creek golfWebb1 mars 2005 · The expression of PHO92 is regulated by Gcr1, and Pho92 is involved in glucose metabolism in Saccharomyces cerevisiae. Kang HJ, Chang M, Kang CM, Park YS, Yoon BJ, Kim TH, Yun CW. Curr Genet, 60(4):247-253, 22 May 2014 Cited by: 5 articles PMID: 24850134 diamond creek golf club membership costWebb24 nov. 2024 · In the nucleus Pho92 associates with target loci through its interaction with transcriptional elongator Paf1C. Functionally, we show that Pho92 promotes and links … diamond creek golf club banner elkWebb22 apr. 2009 · A novel protein, Pho92, has a conserved YTH domain and regulates phosphate metabolism by decreasing the mRNA stability of PHO4 in Saccharomyces cerevisiae. Biochemical Journal 2014, 457 (3) , 391-400. DOI: 10.1042/BJ20130862. diamond creek golf club tee timesWebbDelivery & Pickup Options - 334 reviews of Pho 92 Vietnamese Restaurant "I love pho, but I won't claim to be an expert on what is good and what isn't. This is partially due to the fact that I've always lived in areas where there … circuit city dvd playersWebbYeast PHO92 is homologous to human YTHDF2, and has been used to study disease of metabolism Manually Curated disease of metabolism ( ISS, IGI ) Interaction Details … circuit city east brunswick