Glyoxalase family protein

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August undefined, 2024

The glyoxalase system is a set of enzymes that carry out the detoxification of methylglyoxal and the other reactive aldehydes that are produced as a normal part of metabolism. This system has been studied in both bacteria and eukaryotes. This detoxification is accomplished by the sequential action of two thiol-dependent enzymes; firstly glyoxalase І, which catalyzes the isomerization of the spontaneously formed hemithioacetal adduct between glutathione and 2-oxoaldehydes (such … WebSep 1, 2024 · Although extensive literature exists for some members of this family (e.g., GLO1), little is known about the physiological role of glyoxalase domain-containing protein 4 (GLOD4) and 5 (GLOD5 ...

EF_0656 - Glyoxalase family protein - Enterococcus faecalis …

WebGlyoxalase family protein. Kind. protein. Organism. Bacillus cereus (strain ATCC 14579 / DSM 31) Protein. Name. UniProt ID. Glyoxalase family protein. WebOct 25, 2024 · Conserved Protein Domain Familyglyox_I. ? Lactoylglutathione lyase is also known as aldoketomutase and glyoxalase I. Glyoxylase I is a homodimer in many species. In some eukaryotes, including yeasts and plants, the orthologous protein carries a tandem duplication, is twice as long, and hits this model twice. harvard divinity school field education

Metallo-beta-lactamase protein fold - Wikipedia

WebApr 16, 2016 · The present study identifies the largest family of glyoxalase proteins to date with 41 GmGLYI and 23 GmGLYII members in soybean. Detailed analysis of GmGLYI … WebApr 21, 2024 · Transcriptional regulation of glyoxalase family protein in response to both gibberellic acid (GA) and abscisic acid (ABA) was observed in H vulgare aleurone tissues. The protein was 9.48-fold downregulated by GA … WebAt present the GenBank contains about 700 of amino acid sequences of this enzyme type, and the Protein Data Bank includes dozens of spatial structures. We have offered a … harvard developing child youtube

RCSB PDB - 1ZSW: Crystal Structure of Bacillus cereus Metallo Protein …

CDD Conserved Protein Domain Family: GlxI_Zn - National …

WebMay 9, 2024 · Protein motif identification and gene structure analysis of glyoxalase-like families of grape. The exon-intron structure of the VvGLYI-like, VvGLYII-like and … WebAccordingly, it can be highly advantageous to perform the protein purification and the Glo1 activity assays in MOPS buffers with low salt concentrations instead of phosphate buffers … harvard distribution llcWebSep 2, 2024 · The glyoxalase gene family consists of six structurally and functionally diverse enzymes with broad roles in metabolism. The common feature that defines this family is based on structural motifs that coordinate divalent cations which are required for … harvard dictionary

"WebMar 6, 2007 · Family and domain databases. CDD. cd07233 GlxI_Zn 1 hit; Gene3D. 3.10.180.10 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 1 hit; InterPro. View protein in InterPro; IPR029068 Glyas_Bleomycin-R_OHBP_Dase; ... SSF54593 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 1 hit; " - Glyoxalase family protein

Glyoxalase family protein

Glyoxalase system: A systematic review of its biological activity ...

WebThe MarR/DUF24 Family Regulator QsrR for Quinone Sensing in S. aureus. ... SAV0338 as glyoxalase family protein and SAV2522 as putative thiol-dependent dioxygenase and catE homologue. Hence, QsrR controls similar quinone reductases and dioxygenases in S. aureus that are controlled by the YodB and CatR repressors of B. subtilis (Fig. 13.12). WebProtein knowledgebase. UniParc. Sequence archive. Help. Help pages, FAQs, UniProtKB manual, documents, news archive and Biocuration projects. UniRef. Sequence clusters. Proteomes. Protein sets from fully sequenced genomes. Annotation systems. Systems used to automatically annotate proteins with high accuracy: UniRule (Expertly curated rules)

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WebSep 29, 2024 · PubMed References. pfam00903 is classified as a model that may span more than one domain. pfam00903 is a member of the superfamily cl14632. Sequence … WebGlyoxalase family protein. Status. UniProtKB unreviewed (TrEMBL) Organism. Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB …

WebNov 12, 2024 · The Arabidopsis genome annotation include 11 glyoxalase I (GLXI) genes, all encoding for protein members of the vicinal oxygen chelate (VOC) superfamily. The biochemical properties and physiological … WebFeb 10, 2024 · The enzyme involved is glyoxalase III, also known as DJ-1 protein due to its high sequence similarity with human DJ-1 protein (HsDJ-1). In humans, DJ-1 proteins are associated with early onset of Parkinson disease and it was only later that the presence of glyoxalase III activity was reported in such proteins [ 11 ].

WebThe glyoxalase system is a ubiquitous enzymatic network which plays important roles in biological life. It consists of glyoxalase 1 (GLO1), glyoxalase 2 (GLO2), and reduced glutathione (GSH), which perform an essential metabolic function in cells by detoxifying methylglyoxal (MG) and other endogenous harmful metabolites into non-toxic d-lactate. WebMay 25, 2005 · Glyoxalase family protein: A: 338: Bacillus cereus ATCC 14579: Mutation(s): 0 Gene Names: AAP08011, BC_1024: UniProt: Find proteins for Q81H03 (Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711)) Explore Q81H03 .

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WebSep 1, 2024 · The human glyoxalase family of proteins consists of 6 members varying greatly in enzymatic activity, protein structure, and tissue specificity. This family’s predominant role is the detoxification of reactive dicarbonyls—these proteins have also been shown to regulate a diverse array of physiological processes, including amino-acid ... harvard divinity school logoWebJan 6, 2016 · Discovered more than hundred years back in rabbit and dog tissues, glyoxalase pathway is one of the most ubiquitous and evolutionary well conserved pathway 1,2.The pathway essentially consists of ... harvard definition of crimeWebFeb 10, 2015 · Glyoxalase family protein (GLX) is involved in the conversion of cytotoxic methylglyoxal (MG) into d-Lactate and plays an important role in plant stress tolerance (Chen et al. 2004). In this study, the protein expression of GLX (spot 3) was 2-times higher in Ilmichal and Eolrukchal 1 than in Heukjinjuchal (Fig. ... harvard design school guide to shopping pdfWebJul 15, 2024 · The glyoxalase pathway plays a vital role in the chemical detoxification of methylglyoxal (MG) in biological systems. Our previous study suggested that OsGLYI3 may be effective in seed natural aging. In this study, the rice OsGLYI3 gene was cloned and characterized as specifically expressed in the seed. The accelerated aging (AA) … harvard distributorsWebThese proteins include thiolesterases, members of the glyoxalase II family, that catalyse the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid and a competence protein that is essential for natural transformation in Neisseria gonorrhoeae and could be a transporter involved in DNA uptake. harvard divinity mtsWebGlyoxalase I that uses Zn (++) as cofactor. This family includes eukaryotic glyoxalase I that prefers the divalent cation zinc as cofactor. Glyoxalase I (also known as lactoylglutathione lyase; EC 4.4.1.5) is part of the glyoxalase system, a two-step system for detoxifying methylglyoxal, a side product of glycolysis. harvard divinity school locationWebFamily and domain databases. CDD. cd07237 BphC1-RGP6_C_like 1 hit; cd07252 BphC1-RGP6_N_like 1 hit; Gene3D. 3.10.180.10 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, … harvard distance learning phd