WebJul 17, 2024 · In the European Registry on WATCHMAN Outcomes in Real-Life Utilization medical therapies after device implantation included dual antiplatelet therapy (DAPT) in 60%, vitamin K antagonists in 16%, direct oral anticoagulants (DOACs) in 11%, single antiplatelet therapy in 7%, and no antithrombotic therapy in 6%. WebMay 22, 2024 · Patients with symptomatic PAD should be treated with antithrombotic therapy to reduce cardiovascular risk. Single antiplatelet therapy with either aspirin or clopidogrel is recommended. Patients who undergo revascularization for PAD should be prescribed lifelong antithrombotic therapy.
UpToDate
WebFeb 28, 2024 · In MASTER-DAPT, antiplatelet selection was an investigators’ decision and clopidogrel was used in 53.9% of patients included in shortened DAPT. Recently, HOST-EXAM supported that chronic administration of clopidogrel was superior comparing to aspirin regarding a composite outcome (all-cause mortality, non-fatal MI, stroke, … Webered aspirin did not differ.9 Long-term aspirin therapy, even at a low dose (50 to 162.5 mg/d), may cause overt GI bleeding.10 Risk of GI Complications With Clopidogrel It is unclear how clopidogrel causes GI erosions or ulcerations. Clopidogrel has no effect on the cyclooxygenase pathway and therefore acts indepen-dently of aspirin. In a ... high vs highly
Clopidogrel and Aspirin in Acute Ischemic Stroke and High …
WebAug 4, 2024 · Dual antiplatelet therapy (DAPT) with aspirin and an oral P2Y12 inhibitor such as clopidogrel, ticagrelor, or prasugrel is recommended post percutaneous coronary intervention (PCI) for 6-12 months, depending on stent type and patient-specific factors. 1 In patients requiring temporary interruption of DAPT for procedures or surgeries, … WebSingle antiplatelet therapy (SAPT) with aspirin or clopidogrel reduces the risk of recurrent ischemic stroke in patients with non-cardioembolic ischemic stroke or TIA. However, as … WebMar 27, 2024 · Atrial fibrillation is the most common arrhythmia in the elderly population and is an important cause of stroke. The role of antiplatelet therapy remains controversial. Treatment with aspirin and clopidogrel significantly reduced the rate of stroke in randomised clinical trials. Dual antiplatelet therapy (DAPT) could be an alternative … high vs low absorbance